null
SMILES Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3ccc(cn3)C(F)(F)F)c3OC(C)(C)Cc3c2[nH]1
InChI Key InChIKey=CMVCWCYAFXJCSR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50460544
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair