null

SMILES Oc1c(CN2CCCC2)cc(Nc2ccnc3cc(Cl)ccc23)cc1CN1CCCC1

InChI Key InChIKey=UNJNCKMZXXZIBE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50460929   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460929(CHEMBL167970)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 40 residues) production measured after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38W7JPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£ de Lille

Curated by ChEMBL
LigandPNGBDBM50460929(CHEMBL167970)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells harboring wild type APP695 assessed as reduction in amyloid beta (1 to 42) level after 24 hrs by ELISA met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50GWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Universit£ de Lille

Curated by ChEMBL
LigandPNGBDBM50460929(CHEMBL167970)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells harboring wild type APP695 assessed as reduction in amyloid beta (1 to 40) level after 24 hrs by ELISA met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50GWPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460929(CHEMBL167970)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 42 residues) production measured after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38W7JPubMed