null

SMILES CN(C)CCOc1ccc(Nc2ncc3nc(Sc4ccc(F)cc4)n(C4CCOCC4)c3n2)cc1

InChI Key InChIKey=YVXVVBRYZHAWFN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50461172   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41V28PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41V28PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41V28PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 114nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN494XPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 114nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 189nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Xi'an Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50461172(CHEMBL4228518)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) using poly (Glu, Tyr) as substrate after 40 mins by kinase-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41V28PubMed