null

SMILES Oc1nnn(Cc2ccc(OC(F)(F)F)cc2)c1C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=UOVUCZJYIVHOBC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50462392   

TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)copy SMILEScopy InChI
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed