null

SMILES Clc1cccc(N2CCN(CCCNC(=O)c3ccc4ccccc4c3)CC2)c1Cl

InChI Key InChIKey=KLMXOIOZHMEERQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50462918   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DHGPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3H]5-HT uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DHGPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G42PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G42PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of [3H]serotonin uptake at human SERT expressed in HEK293 cells after 15 to 20 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G42PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462918(CHEMBL4245867)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as reduction in [3H]-NE uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DHGPubMed