null

SMILES CC(=O)C1=C(O)C=C2Oc3c4C(=O)\C(Oc4c(C)c(O)c3[C@@]2(C)C1=O)=C\c1cc(Br)cc(Br)c1

InChI Key InChIKey=GXIWYOAUGDCFNB-XPAZNAPSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463369   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463369(CHEMBL4240521)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured after 20 mins by electrophoresis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463369(CHEMBL4240521)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-tyrosine)-3' as substrate measured after 5 mins by electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463369(CHEMBL4240521)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FVMPubMed