null

SMILES O=C(Nc1ccc(cc1)N1CCC(CC1)C(=O)N1CCOCC1)c1cnc(Oc2ccccc2)nc1

InChI Key InChIKey=NLSSUSRERAMBTA-UHFFFAOYSA-N

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50463722   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataKd:  0.370nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged H-PGDS expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5RJQPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 211nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V4106TPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
RIKEN Center for Biosystems Dynamics Research

Curated by ChEMBL
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed