null

SMILES Cc1ccc(\C=C\c2cccc(c2)-c2nn(c(CC3CC3)c2Cc2ccc(c(F)c2)S(N)(=O)=O)-c2nc(cs2)C(O)=O)s1

InChI Key InChIKey=FBYATYKNYYAWRX-DHZHZOJOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50465091   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LDH (unknown origin) assessed as reduction in lactate production by cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78HWRPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of GS[HiBiT]GS-tagged LDHA (unknown origin) expressed in HEK-293T cells measured after 1 hr by CESTAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))TBA
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JVB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 357nMAssay Description:Inhibition of LDHA in human A673 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of LDHA in human MIA PaCa-2 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465091(CHEMBL4294999 | US11752138, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed