null

SMILES CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ncc(F)cc34)c2c1

InChI Key InChIKey=PMBRUJZGSHBGAZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467981   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467981(CHEMBL4278565)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467981(CHEMBL4278565)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Qpatch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467981(CHEMBL4278565)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed