null

SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccccc2)[nH]c1=O

InChI Key InChIKey=PCGFBWBCNOYCDT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50468819   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase polymerase expressed in Escherichia coli JM109 assessed as decrease in extension of 18 nucleotid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4FZ1PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4FZ1PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468819(CHEMBL4281296)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragmentMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed