null
SMILES Cc1ccc2c(OCCN3CCC(Cc4ccc5OCC(=O)Nc5c4F)CC3)cc(F)cc2n1
InChI Key InChIKey=NNKWTFPUEFVMKD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50477393
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
GlaxoSmithKline
Curated by ChEMBL
GlaxoSmithKline
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [125I]iodosulpiride from human cloned D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [125I]iodosulpiride from human cloned D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Binding affinity at adrenergic beta 1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]ketanserin from human cloned 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Displacement of [3H]mesulergine from human cloned 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair