null

SMILES CCC[C@H](NC1CCc2cc(Cl)ccc2C1)C(=O)Nc1cn(cn1)C(C)(C)CN1CCCC1

InChI Key InChIKey=DHKAZVAQQFUSEE-WCSIJFPASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483764   

TargetPresenilin-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50483764(CHEMBL1770907)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W75PubMed
TargetPresenilin-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50483764(CHEMBL1770907)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W75PubMed