null

SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2ccc(N)nc2)c1F

InChI Key InChIKey=CDDYERXWVMMNOR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484700   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50484700(CHEMBL1945019)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134VMPubMed