null

SMILES COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=WIISKNAPHJLZGS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50493288   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50493288(CHEMBL2426282)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN98KQPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50493288(CHEMBL2426282)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN98KQPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50493288(CHEMBL2426282)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN98KQPubMed