null
SMILES COC(=O)CNc1nc(F)nc(NCCc2ccc(cc2)S(N)(=O)=O)n1
InChI Key InChIKey=VCATWVMENXDNSM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50494035
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant carbonic anhydrase12 transmembrane isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase2 cytosolic isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase7 cytosolic isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2...More data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Inhibition of human recombinant carbonic anhydrase1 cytosolic isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2...More data for this Ligand-Target Pair
Affinity DataKi: 167nMAssay Description:Inhibition of human recombinant carbonic anhydrase6 secreted isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 ...More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Inhibition of human recombinant carbonic anhydrase9 transmembrane isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow...More data for this Ligand-Target Pair
Affinity DataKi: 214nMAssay Description:Inhibition of human recombinant carbonic anhydrase14 transmembrane isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 602nMAssay Description:Inhibition of human recombinant carbonic anhydrase13 cytosolic isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£ degli Studi di Firenze
Curated by ChEMBL
Universit£ degli Studi di Firenze
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Inhibition of human recombinant carbonic anhydrase5A mitochondrial isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 2.74E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase4 membrane-bound isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 6.86E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase3 cytosolic isoform expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2...More data for this Ligand-Target Pair