null

SMILES Fc1ccc(cc1)C(SCC(=O)NCC1CC1)c1ccc(F)cc1

InChI Key InChIKey=HXAYHHZCOCOHSM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50496381   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  6.70E+3nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DMKPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  6.86E+3nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  6.86E+3nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain SERT after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DMKPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  3.54E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  3.54E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetTransporter(Rattus norvegicus (rat))TBA
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  5.76E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

US Patent
LigandPNGBDBM50496381(CHEMBL3126740 | US10913711, Compound 2p | US115550...)copy SMILEScopy InChI
Affinity DataKi:  5.76E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent