null

SMILES CC(C)(O)c1ccnc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1c(F)cccc1Cl

InChI Key InChIKey=MURUMLKNGZQLAO-DEOSSOPVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50500193   

TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500193(CHEMBL3747365)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500193(CHEMBL3747365)copy SMILEScopy InChI
Affinity DataEC50:  5.20E+3nMAssay Description:Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500193(CHEMBL3747365)copy SMILEScopy InChI
Affinity DataKd:  120nMAssay Description:Binding affinity to mouse GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500193(CHEMBL3747365)copy SMILEScopy InChI
Affinity DataKd:  30nMAssay Description:Binding affinity to human GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500193(CHEMBL3747365)copy SMILEScopy InChI
Affinity DataKd:  60nMAssay Description:Binding affinity to rat GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed