null

SMILES Clc1ccccc1[C@@H](NS(=O)(=O)c1ccc2OCCCOc2c1)c1cc2ccccc2s1

InChI Key InChIKey=TYGYAUYMFQMBTE-XMMPIXPASA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50500205   

TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500205(CHEMBL3746456)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500205(CHEMBL3746456)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human glucokinase by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500205(CHEMBL3746456)copy SMILEScopy InChI
Affinity DataKd:  19nMAssay Description:Binding affinity to human GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500205(CHEMBL3746456)copy SMILEScopy InChI
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BZPPubMed