null

SMILES NC(=O)c1cccc2C(=O)\C(Oc12)=C\c1ccc(cc1)C(=O)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key InChIKey=MABHSRSWSCMJOM-YBEGLDIGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50501830   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM50501830(CHEMBL4519178)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156WFPubMed