null

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)cc1

InChI Key InChIKey=TYOXUGIRRHOAMB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50502407   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50502407(CHEMBL4549060 | US11084784, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inverse agonist activity at RORC2 in human Th17 cells assessed as inhibition of IL-17A secretion incubated for 4 days by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V64PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50502407(CHEMBL4549060 | US11084784, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:CHO-K1 cells stably transfected with RORĪ³t are maintained in MEM-EBS with 5% FBS, 1% penicillin streptomycin solution and 1 mg/mL G418. The cells ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60S6KUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50502407(CHEMBL4549060 | US11084784, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inverse agonist activity at human biotinylated HN-Avi-MBPS-TCS-RORC2 (258 to 518 residues) assessed as recruitment of SRC-1-derived coactivator measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736V64PubMed