null

SMILES CN(C)[C@H]1CCN(C1)C(=O)c1nc(-c2ccc(C#N)c(F)c2)n(c1C)-c1cc2cn(C)nc2cc1F

InChI Key InChIKey=HRJKSLAMWDUOAR-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50503513   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50503513(CHEMBL4453520 | US10626103, Example 48)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as induction of CD11b expression after 4 days by LIVE/DEAD violet staining based FACS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DFGPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50503513(CHEMBL4453520 | US10626103, Example 48)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4TRB
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM50503513(CHEMBL4453520 | US10626103, Example 48)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DFGPubMed