null
SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)Cc4nccnc4[C@@](C)(CO)[C@]3([H])CC[C@@]12C)C(=O)OCc1ccccc1
InChI Key InChIKey=QGZAUUKJIJZEAS-MQLGQBSPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50506874
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human MCF-7T cells assessed as reversal of resistance to vincristine-induced cytotoxicity...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Reversal of P-glycoprotein mediated multidrug resistance in human KBV cells assessed as reversal of resistance to vincristine-induced cytotoxicity by...More data for this Ligand-Target Pair