null
SMILES CC1(C)C[C@@H](CCS1(=O)=O)c1c[nH]c2c(cc(cc12)-c1ccc(F)cc1)C(N)=O
InChI Key InChIKey=YGYGASJNJTYNOL-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50507355
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.
Curated by ChEMBL
GlaxoSmithKline Inc.
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of IKKbeta in human CD14-positive monocytes assessed as reduction in LPS-stimulated TNFalpha secretion preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.
Curated by ChEMBL
GlaxoSmithKline Inc.
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged IKKbeta (1 to 737 residues) expressed in baculovirus expression system using GST-IkBalpha subst...More data for this Ligand-Target Pair