null

SMILES COc1cc2ncnc(Nc3ccc(NC(=O)C=C)cc3)c2cc1OCCN1CCOCC1

InChI Key InChIKey=VHCZHJHCTYDXLJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50510886   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50510886(CHEMBL4516586)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R/T790M mutant (catalytic domain 695 to end) expressed in baculovirus-infected Sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50510886(CHEMBL4516586)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50510886(CHEMBL4516586)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant GST-tagged EGFR (catalytic domain 695 to end) expressed in baculovirus-infected Sf9 cells assessed as reduction in ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50510886(CHEMBL4516586)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed