null
SMILES COc1cc2ncnc(Nc3ccc(NC(=O)C=C)cc3)c2cc1OCCN1CCOCC1
InChI Key InChIKey=VHCZHJHCTYDXLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50510886
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R/T790M mutant (catalytic domain 695 to end) expressed in baculovirus-infected Sf9 cells assessed...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant GST-tagged EGFR (catalytic domain 695 to end) expressed in baculovirus-infected Sf9 cells assessed as reduction in ph...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Arromax Pharmatech Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair