null

SMILES CCn1ncc(c1C)-c1nc2c(NC3CN(C3)C(=O)C3CCOCC3)ncnc2n1C

InChI Key InChIKey=CDHAOCUUOAMMOI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50512311   

LigandPNGBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI
Affinity DataIC50: 453nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed