null
SMILES COc1cc(ccc1Nc1cc(ccn1)N1CCC[C@@H](C1)C(=O)NCc1ccc(OC(F)(F)F)cc1)N1CCC(CC1)N1CCOCC1
InChI Key InChIKey=KZDFKXHSGQQXNG-SANMLTNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50513568
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2347 residues) expressed in baculovirus system assessed as decrea...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 558nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 1620 residues) expressed in baculovirus system assessed as decreas...More data for this Ligand-Target Pair