null

SMILES O=C(NCc1cccc(Cn2cnc3ccccc23)c1)c1cc2ccccc2[nH]1

InChI Key InChIKey=QKILOFWGQYDRGO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50514760   

TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of mouse TDO transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human DAN-G cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed