null
SMILES CC(C)(C)NC(=O)[C@@H](N(Cc1ccc(OCc2ccccc2Br)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O
InChI Key InChIKey=ZYUXHGXGYZXKTO-MHZLTWQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50515604
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
Affinity DataKi: 6.76E+3nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant MDMX (18 to 111 residues) expressed in Escherichia coli BL21 (DE3) cells measured after 30 ...More data for this Ligand-Target Pair