null
SMILES CCc1sc2ncnc(N[C@@H](Cc3ccccc3)C(O)=O)c2c1-c1cccc(Oc2ccc(F)cc2)c1
InChI Key InChIKey=IAYHNWPUEMDPER-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50519032
TargetBcl-2-like protein 1(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from human N-terminal thrombin cleavage site-fused/His6-tagged Bcl-2 expressed in Es...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKi: 7.70E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair