null

SMILES CCc1sc2ncnc(N[C@@H](Cc3ccccc3)C(O)=O)c2c1-c1cccc(Oc2ccc(F)cc2)c1

InChI Key InChIKey=IAYHNWPUEMDPER-QHCPKHFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519032   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519032(CHEMBL4450255)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0CPHPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519032(CHEMBL4450255)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from human N-terminal thrombin cleavage site-fused/His6-tagged Bcl-2 expressed in Es...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0CPHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519032(CHEMBL4450255)copy SMILEScopy InChI
Affinity DataKi:  7.70E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0CPHPubMed