null

SMILES Nc1cc(ccc1F)-c1nc(nc(n1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCOCC1

InChI Key InChIKey=GVYMJINRDOCUNO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520030   

LigandPNGBDBM50520030(CHEMBL4436366)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50520030(CHEMBL4436366)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of biotinylated NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QPDPubMed