null

SMILES C[C@@H]1CN(c2cn(C)c3cc(ccc23)C(O)=O)C(=O)c2c(CCCOc3cc(C)c(Cl)c(C)c3)c3ccc(Cl)c(-c4c(C)nn(C)c4C)c3n12

InChI Key InChIKey=XEJDPJHQCIGMPE-JOCHJYFZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50521465   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521465(CHEMBL4449014 | US11596639, Example 88)copy SMILEScopy InChI
Affinity DataKi:  0.0810nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P04PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521465(CHEMBL4449014 | US11596639, Example 88)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs in presence of 1% fetal bovine serum by TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P04PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521465(CHEMBL4449014 | US11596639, Example 88)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:Fluorescence Polarization Anisotropy Competition Assay. Anisotropy measurements were carried out in 384-well, black, flat-bottom plates (Greiner Bio-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028WFXUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521465(CHEMBL4449014 | US11596639, Example 88)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to Bcl-2 (unknown origin) after 0.5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P04PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50521465(CHEMBL4449014 | US11596639, Example 88)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to Bcl-xL (unknown origin) after 0.5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P04PubMed