null

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cnn3CCCCc23)nc1

InChI Key InChIKey=PDAGDCQXFVQYJZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521930   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521930(CHEMBL4447396)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of human full length GST-tagged CDK4 (1 to 303(end) amino acids)/Cyclin D3 (1 to 292(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C250VTPubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521930(CHEMBL4447396)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human full length GST-tagged CDK6 (1 to 326(end) amino acids)/Cyclin D3 (1 to 292(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C250VTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521930(CHEMBL4447396)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of human full length GST-tagged CDK2 (1 to 298(end) amino acids)/Cyclin E1 (1 to 410(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C250VTPubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521930(CHEMBL4447396)copy SMILEScopy InChI
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C250VTPubMed