null

SMILES Nc1nc2ncccc2[nH]1

InChI Key InChIKey=KXQPVJRJUJJWQJ-UHFFFAOYSA-N

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524488   

TargetBeta-secretase 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN991ZPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair