null
SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCOCC4)c4OCCOc4c23)cc1)C(F)(F)F
InChI Key InChIKey=SZSDKEQZCBOVMW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50524586
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
Affinity DataIC50: 275nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED
US Patent
Affinity DataIC50: 275nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:1. Dilution of the compound: a total of 12 concentrations were obtained using a 4-fold gradient dilution from the highest concentration of 10000 nM (...More data for this Ligand-Target Pair