null

SMILES COc1cc2c(Nc3ccc(NC(=O)C(N4Cc5ccccc5C4=O)c4cc(F)ccc4F)cc3F)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=RNUUQLALKWVVSI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50525411   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525411(CHEMBL4443483)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of EGFR 19D/T790M/C797S mutant (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30ZXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525411(CHEMBL4443483)copy SMILEScopy InChI
Affinity DataIC50: 331nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525411(CHEMBL4443483)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525411(CHEMBL4443483)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) T790M/L858R/C797S mutant expressed in baculov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30ZXPubMed