null

SMILES CCOc1ccccc1-n1nnnc1SCC(=O)Nc1cc(nn1-c1ccccc1)C(C)(C)C

InChI Key InChIKey=BGUYPHQCUACHCL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525727   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525727(CHEMBL4573099)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkA transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525727(CHEMBL4573099)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkB transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525727(CHEMBL4573099)copy SMILEScopy InChI
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human His-tagged TrkA kinase domain (441-796 residues) expressed in baculovirus expression system incubated with enzyme/ATP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed