null
SMILES CCOc1cc(ccc1Nc1ncc2N(C)C(=O)[C@@H](CC)N(Cc3ccccc3)c2n1)C(=O)NC1CCN(C)CC1
InChI Key InChIKey=LYAOPUXRPJKSKW-RUZDIDTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50526303
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of PLK1 (unknown origin) using Ser/Thr 16 as substrate after 60 mins by Z-LYTE activity assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataKd: 69nMAssay Description:Binding affinity to BRD4 (unknown origin) by isothermal calorimetryMore data for this Ligand-Target Pair