null
SMILES Cc1cc(NC(=O)Nc2cc(nn2-c2ccccc2)C(C)(C)C)ccc1-c1cnc(NC2CC2)c2nccn12
InChI Key InChIKey=LEVZCGPPIDIGHW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50529793
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in liver microsomes (unknown origin) using (+/-) N-3-benzylnirvanol as substrate preincubated for 5 mins followed by NADPH addi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of CYP3A4 in liver microsomes (unknown origin) using ketoconazole as substrate preincubated for 5 mins followed by NADPH addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 in liver microsomes (unknown origin) using alpha-naphthoflavone as substrate preincubated for 5 mins followed by NADPH addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP2C9 in liver microsomes (unknown origin) using sulfaphenazole as substrate preincubated for 5 mins followed by NADPH addition and me...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chung-Ang University
Curated by ChEMBL
Chung-Ang University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of CYP3A4 in liver microsomes (unknown origin) using ketoconazole as substrate preincubated for 5 mins followed by NADPH addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP2C9 in liver microsomes (unknown origin) using sulfaphenazole as substrate preincubated for 5 mins followed by NADPH addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in liver microsomes (unknown origin) using (+/-) N-3-benzylnirvanol as substrate preincubated for 5 mins followed by NADPH addi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2B6 in liver microsomes (unknown origin) using clopidogrel as substrate preincubated for 5 mins followed by NADPH addition and measu...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chung-Ang University
Curated by ChEMBL
Chung-Ang University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Homo sapiens (Human))
Chung-Ang University
Curated by ChEMBL
Chung-Ang University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Homo sapiens (Human))
Chung-Ang University
Curated by ChEMBL
Chung-Ang University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2B6 in liver microsomes (unknown origin) using clopidogrel as substrate preincubated for 5 mins followed by NADPH addition and measu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 in liver microsomes (unknown origin) using alpha-naphthoflavone as substrate preincubated for 5 mins followed by NADPH addition ...More data for this Ligand-Target Pair