null

SMILES O=C(NCCN1CCOCC1)Nc1nc2ccc(Sc3nnc4ccc(NC5CC5)nn34)cc2s1

InChI Key InChIKey=MRFFMALERXPRTF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50532762   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CYP3A4 co-expressed with human P450 reductase and human b5 reductase assessed as reduction in 7-Hydroxyquinoline prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CYP3A4 co-expressed with human P450 reductase and human b5 reductase assessed as reduction in 7-Hydroxyquinoline prod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 274nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sanofi-Aventis Germany GmbH

Curated by ChEMBL
LigandPNGBDBM50532762(CHEMBL4513820)copy SMILEScopy InChI
Affinity DataIC50: 274nMAssay Description:Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HW4PubMed