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SMILES COc1cccc(OC)c1-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1

InChI Key InChIKey=RLSSIMDTXVXYRT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50533372   

TargetIntegrase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533372(CHEMBL4454510)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV integrase pre-incubated for 10 mins before addition of oligo-5'-biotin ATGTGGAAAATCTCTAGCA annealed with ACTGCTAGAGATTTTCCACAT 3'-C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533372(CHEMBL4454510)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533372(CHEMBL4454510)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533372(CHEMBL4454510)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533372(CHEMBL4454510)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6B8PPubMed