null

SMILES CSc1ccc2cc(ccc2c1)[C@@H](C)C(O)=O

InChI Key InChIKey=DZFJDDMBLJXLJL-SECBINFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533573   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z47WNPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 4.35E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z47WNPubMed