null

SMILES ONC(=O)\C=C\c1ccc(cc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(Br)cc1

InChI Key InChIKey=IKVGYSSTVXNKDM-VGOFMYFVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537474   

TargetHistone deacetylase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50537474(CHEMBL4542734)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50537474(CHEMBL4542734)copy SMILEScopy InChI
Affinity DataIC50: 423nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50537474(CHEMBL4542734)copy SMILEScopy InChI
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50537474(CHEMBL4542734)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50537474(CHEMBL4542734)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed