null
SMILES Cl.[H][C@]12C[C@@]1([H])N[C@@H](COc1ccc(Cl)nc1)C2
InChI Key InChIKey=VZIQKVIAFWXNFL-GZJXKWBNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50538040
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Suven Life Sciences Ltd.
Curated by ChEMBL
Suven Life Sciences Ltd.
Curated by ChEMBL
Affinity DataKi: 329nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in CHOK1 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Suven Life Sciences Ltd.
Curated by ChEMBL
Suven Life Sciences Ltd.
Curated by ChEMBL
Affinity DataKi: 525nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in IMR32 cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 min in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 min in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair