null

SMILES CCN1CCN(CC1)C(=O)Nc1cc(ccn1)-c1cn(C2CCOCC2)c2cnccc12

InChI Key InChIKey=SAZIAQSVBIWIDU-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50538099   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by Qpatch S8 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 I (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 II (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed