null

SMILES C[C@@H]1CNC[C@@H](Cc2c(C)cc(Cl)cc2-c2ccnc3cc(CN4C(=O)C5CC5C4=O)sc23)O1

InChI Key InChIKey=JLPZIAGJKHDMOQ-SYJVCXSYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538578   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
RAPT Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50538578(CHEMBL4640729)copy SMILEScopy InChI
Affinity DataEC50:  60nMAssay Description:Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K2TPubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
RAPT Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50538578(CHEMBL4640729)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:Inhibition of recombinant full length USP7 (unknown origin) using ubiquintin-rhodamine as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K2TPubMed