null

SMILES CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1

InChI Key InChIKey=QLLZULWFESFQOY-GFCCVEGCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50538681   

TargetHistamine H4 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-histamine from Galphai2/Gbeta1gamma2-coupled human recombinant H4R expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed