null

SMILES CC(C)(C)CNc1nccc(n1)N1CCc2nc[nH]c2C1

InChI Key InChIKey=GYJOUMCDNZCUAE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50538682   

TargetHistamine H3 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataKi:  0.537nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H3R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from Galphai2/Gbeta1gamma2-coupled human recombinant H3R expressed in baculovirus infected Sf9 insect ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-histamine from Galphai2/Gbeta1gamma2-coupled human recombinant H4R expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HZ1PubMed