null

SMILES FC(F)Oc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2ccnc3cc(F)cnc23)n1-c1ccccc1F

InChI Key InChIKey=DYMJRWLCTOEALR-KOMQPUFPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541712   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50541712(CHEMBL4640917 | US11926614, Example 183)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 20 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22SXPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50541712(CHEMBL4640917 | US11926614, Example 183)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50541712(CHEMBL4640917 | US11926614, Example 183)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TNKS1/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by dual-glo lucifer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22SXPubMed