null

SMILES CC(C)N(C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccc(cc1)C(=O)NO

InChI Key InChIKey=JVCQXJCACOCTST-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50542229   

TargetHistone deacetylase 3(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal His-tagged and N-terminal GST-tagged full length human HDAC3 expressed in baculovirus expression system co-expressed with hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human HDAC6 expressed in baculovirus expression system using FAM-RHKK(Ac)-NH2 substrate incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC8 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataKd:  3.5nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Binding affinity to human HDAC8 pre-incubated for 10 mins before FITC-M344 addition and measured after 10 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066residues) expressed in baculovirus expression system using FAM-RHK(TF-Ac)-NH2 substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human HDAC2 expressed in baculovirus expression system using FAM-TSRHK(Ac)KL-NH2 substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal GST-tagged human HDAC4 (101 to 1084 resides) expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC5 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC10 expressed in baculovirus expression system using FAM-TSRHK(Ac)KL-NH2 substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542229(CHEMBL4642821)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG and His-tagged full length human HDAC1 expressed in baculovirus expression system using FAM-TSRHK(Ac)KL-NH2 substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC1470PubMed