null

SMILES COc1c(ccc(O[C@@H](C)C(F)(F)F)c1C(=O)N1CC(C1)c1ccc(cc1)C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=JCXDGAMFXUHQBI-LBPRGKRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543918   

TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543918(CHEMBL4646639)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29027C0PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543918(CHEMBL4646639)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology QPatch assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29027C0PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50543918(CHEMBL4646639)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human GlyT1 expressed in human HEK cells assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29027C0PubMed